Paxlovid

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what we prescribe

  • Paxlovid consists of nirmatrelvir, which inhibits a SARS-CoV-2 protein to stop the virus from replicating, and ritonavir, which slows down nirmatrelvir’s breakdown to help it remain in the body for a longer period at higher concentrations.
  • Indicated for patients with positive results of direct SARS-CoV-2 testing.
  • Recommend for symptomatic patients who have mild to moderate COVID-19 and risk factors for progression to severe disease.

Contraindication

Paxlovid is not authorized in the following setting:

  • Prevention of COVID-19.
  • Patient under 50 yrs with no risk factors or underlying medical conditions.
  • In those requiring hospitalization due to severe COVID-19.
  • Paxlovid is not a substitute for vaccination.
  • Individuals who have SARS-CoV-2 infection but do NOT have symptioms.
  • Individuals without any risk factors for progression to severe disease.

Warning

  • Possible side effects of Paxlovid include impaired sense of taste, diarrhea, high blood pressure and muscle aches.
  • May result in potentially significant drug interactions if used at the same time as certain other drugs.
  • May lead to HIV-1 drug resistance in people with uncontrolled or undiagnosed HIV-1 infection.
  • Paxlovid is not recommended in patients with severe kidney and liver impairment.

Paxlovid Requirements

NOTE: Paxlovid can only be prescribed if you meet ALL of the following requirements:

  • Age 30+.
  • Positive for COVID-19.
  • If you have underlying medical conditions such as hypertension, diabetes, heart condition, lung disease.

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